News

News

  • ADAPTABLE Reaches Enrollment Milestone of 5,000 Participants

    Enrollment for the Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-Term Effectiveness (ADAPTABLE) study has reached 5,000 participants. With its coordinating center based at the Duke Clinical Research Institute, the ADAPTABLE study is a large three-year pragmatic trial assessing two different doses of aspirin – 81mg and 325mg – to evaluate which dose is more effective ...
  • Engagement, Research, and Evidence

    ADAPTABLE is leading the way in patient-researcher partnerships.  A recent example of this collaboration is an insightful perspective piece for Circulation authored by Adrian Hernandez, ADAPTABLE Study Co-PI, and Henry Cruz, a patient Adaptor. Hernandez and Cruz discuss the need for and benefits of a national learning health system and how PCORnet, The National Patient-Centered Research Network is ...
  • ADAPTABLE Study: Patient-Researcher Partnerships Produce Better Outcomes

    Amidst large vendor booths showcasing the latest advances in cardiovascular innovation at the 66th Annual American College of Cardiology Scientific Session and Expo, Henry Cruz and Tom McCormick, patient partners on the ADAPTABLE Study team, answered questions at the CardioSmart Patient Engagement Pavilion and later participated in a panel discussion on leveraging patient engagement to ...
  • NEJM Highlights How the ADAPTABLE Study is Changing Clinical Research

    ADAPTABLE’s electronic consent processes and web-based design are featured in a multi-part review article by the New England Journal of Medicine on The Changing Face of Clinical Trials. New approaches to informed consent and innovative options for obtaining it have come about from technological advances and pragmatic research designs. While answering the question of what is ...
  • ADAPTABLE Advances Groundbreaking Patient Engagement Model

    February is ADAPTABLE’s time to shine. The groundbreaking pragmatic clinical trial coordinated by the Duke Clinical Research Institute, ADAPTABLE is comparing the effectiveness of two different daily doses of aspirin widely used to prevent heart attacks and strokes in individuals living with heart disease. The study is funded through a PCORI grant and is the first ...
  • An Aspirin a Day—But What’s the Best Dose?

    In a new PCORI blog post recognizing American Heart Month, research partners Adrian Hernandez and Henry Cruz describe the progress and strengths of the ADAPTABLE Study. ADAPTABLE aims to improve the health of people with heart disease, but also to show what’s possible when you have an engaged community using a resource such as PCORnet ...
  • ADAPTABLE Study Reaches 1,000 Participant Milestone

    On January 25, 2017 the ADAPTABLE Study randomized its 1000th  patient, an accomplishment resulting from patient partners, researchers, and clinicians coming together to “think big.” Reaching this milestone demonstrates the power of using novel ideas and creative collaborations to reach and engage participants. The ADAPTABLE study will enroll and follow as many as 20,000 participants with heart disease ...
  • 2016 Year in Review: An Opportunity to Reflect on Highlights and Groundbreaking Accomplishments

    As the year comes to a close, the ADAPTABLE Study team would like to wish everyone a happy, healthy, and safe holiday and all the best in the New Year. This year has been a memorable year for ADAPTABLE and we would like to take a moment to reflect on accomplishments during 2016, several of which ...
  • Facebook Live Broadcast: What is the Optimal Dose of Aspirin for Patients with Heart Disease?

    In conjunction with The American Heart Association  2016 Scientific Sessions and REACHnet CDRN Health in Our Hands Network,  ADAPTABLE will be live on Facebook on November 15 at 10:15 CST. Co-Principal Investigator, Dr. Matthew Roe, and patient participant, Ken Grigoire, will answer your questions about ADAPTABLE, a study that seeks to understand what is the optimal dose ...
  • ADAPTABLE Study Kick-Off Meeting: Determining the Path Forward for ADAPTABLE and Pragmatic Research

    Patient leaders, study investigators, and operations and research staff gathered together on October 28, 2016 in Washington D.C. to discuss ideas and strategies for making this novel, pragmatic study a success.

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