The OneFlorida Clinical Data Research Network (CDRN) led by Principal Investigator, Carl Pepine will now be participating in ADAPTABLE and joining efforts with the other seven CDRNs to enroll 20,000 participants in this novel research study. Similar to the other CDRNs participating in ADAPTABLE, OneFlorida is a collaboration of researchers, clinicians, and patients who work together to conduct research to answer questions that matter most to patients and those who care for them.
ADAPTABLE is designed to compare the effectiveness of two daily doses of aspirin widely used to prevent heart attacks and strokes in individuals living with heart disease. The study hopes to generate results that will improve care and outcomes for patients with heart disease. Using electronic health records (EHRs) and web-based technology, participants will self-consent, self-randomize and report data directly through an online portal. In addition, with participants’ consent, electronic health information captured during routine care will be used to identify events that will provide ADAPTABLE researchers with additional health outcomes data to inform better decision-making.
The ADAPTABLE study is funded through a Patient-Centered Outcomes Research Institute (PCORI) Award (Contract Number: ASP-1502-27079). ADAPTABLE is the first demonstration project to be conducted through PCORnet, the National Patient-Centered Clinical Research Network. PCORnet is a PCORI-funded initiative designed to improve the nation’s capacity to conduct comparative clinical effectiveness research. More information about PCORnet can be found here.